40283-41-8, 2-Aminothiazole-4-carboxylic acid is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Preparation of 2-chlorothiazole-4-carboxylic acid To a solution of 2.84 g (19.7 mmol) of 2-aminothiazole-4-carboxylic acid in 30 ml of 1,4-dioxane was added 50 ml of concentrated hydrochloric acid, followed by cooling to 0C, and 10 ml of an aqueous solution of 2.04 g (29.6 mmol) of sodium nitrite was added charged dropwise thereto at 0C to 5C. The reaction liquid was stirred at 0C for 2 hours, and then 2.93 g (29.6 mmol) of copper chloride was charged in separate portions thereto. The reaction liquid was returned to room temperature, followed by stirring for 8 hours. To the reaction liquid were added water and ethyl acetate, followed by extraction with ethyl acetate four times. The organic layer was washed with saturated brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to prepare 1.77 g (yield 55%) of a target compound. 1H-NMR (DMSO-d6, ppm) delta 8.41 (1H, s). The proton of the carboxylic acid was not detected., 40283-41-8
As the paragraph descriping shows that 40283-41-8 is playing an increasingly important role.
Reference：
Patent; Mitsui Chemicals Agro, Inc.; EP2319830; (2011); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica