3622-35-3, Benzo[d]thiazole-6-carboxylic acid is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: A mixture of 1-12 (0.27 g, 0.001 mol) and 2,6-dimethylisonicotinic acid (0.16 g, 0.001 mol) in DCM (10 mL) was treated with DIPEA (0.69 mL, 0.75 g/mL, 0.004 mol) and HBTU (0.38 g, 0.001 mol). Stirring was continued for 16 h. The RM was diluted with water (5 mL), acidified with 1 M HC1 until pH~3 and the layers were separated and the OL was washed with 1 M NaOH until pH~9, water, then dried over MgS04, filtered and concentrated in vacuo to give an oil (0.8 g). A purification was performed via Prep HPLC (stationary phase: RP XBridge Prep C18 OBD-IotaOmicronmuiotaeta, 50 xl50mm, mobile phase: 0.25% NH4HCO3 solution in water, MeOH) yielding two fractions. A purification was performed using Prep SFC (stationary phase: Chiralpak Diacel AD 20 x 250 mm, mobile phase: C02, EtOH with 0.4% iPrNH2) yielding 4 fractions of which two afforded compounds lb (64 mg, 18%) and la (70 mg, 19%)., 3622-35-3
As the paragraph descriping shows that 3622-35-3 is playing an increasingly important role.
Reference：
Patent; JANSSEN PHARMACEUTICA NV; VAN ROOSBROECK, Yves, Emiel, Maria; VAN DEN KEYBUS, Frans, Alfons, Maria; TRESADERN, Gary, John; BUIJNSTERS, Peter, Jacobus, Johannes, Antonius; VELTER, Adriana, Ingrid; JACOBY, Edgar; MACDONALD, Gregor, James; GIJSEN, Henricus, Jacobus, Maria; AHNAOU, Abdellah; DRINKENBURG, Wilhelmus, Helena, Ignatius, Maria; (216 pag.)WO2018/83098; (2018); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica