939-69-5, 6-Hydroxybenzo[d]thiazole-2-carbonitrile is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
939-69-5, The mixture of 6-hydroxy-2-cyanobenzothiozole(0.311 g, 1.77 mmol), 3-chloropropyldimethylamine hydrochloride (0.36 g, 2.27 mmol), potassium carbonate (0.63g, 4.57 mmol) and sodium iodide (0.034 g) in acetone (30 ml) was heated to reflux overnight. Upon cooling to roomtemperature, the insoluble solid was removed by filtration. The compound was purified by flash chromatography usingmethylene chloride/methanol (96:4) as eluent in a yield of 86percent (0.387 g).1H NMR (CD2Cl2): 7.98 (d, J= 9.3 Hz, 1H), 7.32 (d, J= 2.4 Hz, 1H), 7.16 (dd, J = 9.0 Hz, J= 2.1 Hz, 1H), 4.04 (t, J = 6.4Hz, 2H, OCH2), 2.36 (t, J = 7.2 Hz, 2H, NCH2), 2.13 (s, 6H, CH3), 1.90 (m, 2H, CH2).
As the paragraph descriping shows that 939-69-5 is playing an increasingly important role.
Reference:
Patent; Promega Corporation; Cali, James J.; Daily, William; Hawkins, Erika; Klaubert, Dieter; Liu, Jianquan; Meisenheimer, Poncho; Scurria, Michael; Shultz, John W.; Unch, James; Wood, Keith V.; Zhou, Wenhui; Valley, Michael P.; (202 pag.)EP2277872; (2016); B1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica