With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15864-32-1,2-Amino-6-bromobenzothiazole,as a common compound, the synthetic route is as follows.
To a stirred solution of 6-bromobenzo[d]thiazol-2-amine (2.50 g, 10.7 mmol) and DMAP (1.33 g, 12.8 mmol) in 20 mL CH2Cl2 at 0 C, was added acetic anhydride (1.23 mL, 13.0 mmol) in 5 mL CH2Cl2 dropwise. The reaction mixture was stirred at room temperature for 12 h before 1 N HCl (20 mL) was added. After filtrated, the precipitate was washed with H2O and dried in vacuum to give the title compound (2.30 g, 79%) as a white solid., 15864-32-1
15864-32-1 2-Amino-6-bromobenzothiazole 85149, athiazole compound, is more and more widely used in various fields.
Reference：
Article; Yang, Zhaohui; Ma, Haikuo; Sun, Zhijian; Luo, Lusong; Tian, Sheng; Zheng, Jiyue; Zhang, Xiaohu; Bioorganic and Medicinal Chemistry Letters; vol. 25; 17; (2015); p. 3665 – 3670;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica