133692-16-7, 2-Amino-5-bromo-4-methylthiazole hydrochloride is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
EXAMPLE 64 A mixture of 2-amino-5-bromo-4-methylthiazole hydrochloride (1.15 g), 2-mercaptopyrimidine (0.6 g) and potassium carbonate (1.7 g) in N,N-dimethylformamide (20 ml) was heated at 90 C. for 3.5 hours with stirring. The reaction mixture was poured into ice water. The mixture was extracted with a mixture of tetrahydrofuran and ethyl acetate (1:1), washed with aqueous saturated sodium chloride and dried over magnesium sulfate. The solvent was concentrated under reduced pressure to give solid. The solid was subjected to column chromatography on silica gel (silica gel 60, 70-230 mesh,; Merck: 100 g) and eluted with a mixture of chloroform and methanol (10:1). The fractions containing the objective compound were combined and concentrated under reduced pressure to give 2-amino-4-methyl-5-(2-pyrimidinylthio)thiazole (0.65 g, yield: 58.0%). mp: 165-170 C. (dec.) IR (Nujol): 3300, 3175, 1630, 1555, 1490, 1320 cm-1 NMR (DMSO-d6, 200 MHZ, ppm): 2.10 (3H, s), 7.24-7.33 (1H, m), 7.33 (2H, s), 8.64 (2H, d, J=5Hz) Mass: M+1 225, M 224, m/e 209, 191, 182, 166, 145, 133692-16-7
As the paragraph descriping shows that 133692-16-7 is playing an increasingly important role.
Reference：
Patent; Fujisawa Pharmaceutical Co., Ltd.; US5256675; (1993); A;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica