Brief introduction of 942631-50-7

942631-50-7 tert-Butyl thiazol-5-ylcarbamate 53432624, athiazole compound, is more and more widely used in various fields.

942631-50-7, tert-Butyl thiazol-5-ylcarbamate is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

942631-50-7, [0003 10] Synthesis of thiazol-5-amine hydrochloride (380): To a stirred solution of compound 379 (300 mg, 1.5 mmol) in MeOH (5 mL) was added 4 N HC1 in 1, 4-Dioxane (5 mL) under argon atmosphere at 0 C; warmed to RT and stirred for 3 h. The reaction was monitored by TLC; after completion of the reaction, the volatiles were removed in vacuo to obtain the crude. The crude was washed with n-pentane (2 x 5 mL) and dried in vacuo to afford compound 380 (150 mg, HC1 salt) as pale yellow solid. TLC: 50% EtOAc/ hexanes (R 0.1); 1H-NMR (DMSO-d6, 500 MHz): oe 9.10 (s, 1H), 7.22 (s, 1H).

942631-50-7 tert-Butyl thiazol-5-ylcarbamate 53432624, athiazole compound, is more and more widely used in various fields.

Reference:
Patent; INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION; ASSEMBLY BIOSCIENCES, INC.; TURNER, William W.; ARNOLD, Lee Daniel; MAAG, Hans; ZLOTNICK, Adam; WO2015/138895; (2015); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica