With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2942-14-5,5-Methoxybenzo[d]thiazole,as a common compound, the synthetic route is as follows.
Intermediate 25:[0144] A mixture of intermediate 24 (272 mg, 1.65 mmol) and hydroiodic acid (45%, 2 mL) was heated to reflux for 5 h. The mixture was diluted with water and filtered. The filtrate was neutralized and the solids were filtered, washed with water, and combined to give benzo[c ]thiazol-5-ol (intermediate 25) (206 mg, 83%). HPLC: 99%, RT 2.038 min. MS (ESI) m/z 152.1 [M + H]+., 2942-14-5
2942-14-5 5-Methoxybenzo[d]thiazole 12422200, athiazole compound, is more and more widely used in various fields.
Reference:
Patent; THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL; JIN, Jian; ROTH, Bryan; FRYE, Stephen; WO2012/3418; (2012); A2;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica