With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.15864-32-1,2-Amino-6-bromobenzothiazole,as a common compound, the synthetic route is as follows.
Example 10; Preparation of 7V-(6-Phenylbenzo[]thiazol-2-yl)acetamide (10); [0386] A mixture of 6-bromobenzo[d]thiazol-2-amine (61.7 mg, 0.27 mmol), phenylboronic acid (49 mg, 0.40 mmol), PddppfCl2-DCM (cat.) in NaHCO3 (sat., 0.75 mL) and 1,4-dioxane (1.5 mL) was heated in a microwave at 130 0C for 30 min. The reaction mixture was purified on HPLC to give the corresponding amine (54 mg, 89%) as a white solid., 15864-32-1
The synthetic route of 15864-32-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; TAKEDA PHARMACEUTICAL COMPANY LIMITED; DONG, Qing; GONG, Xianchang; HIROSE, Masaaki; JIN, Bohan; ZHOU, Feng; WO2010/8847; (2010); A2;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica