939-69-5, 6-Hydroxybenzo[d]thiazole-2-carbonitrile is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
939-69-5, To the solution of benzene sulfonyl chloride derivative (0.7 g, 2.98 mmol) and 2-cyano-6-hydroxoylbenzothiazole or 2-cyano-6-hydroxyquinoline (2.84 mmol) in 10 ml of dry methylene chloride, triethylamine (0.58 g, 5.68 mmol) at room temperature was added, and the resultant mixture stirred for 3 hours. The product was purified by flash chromatography using heptane/methylene chloride (1/2) as eluent. (yield 85percent): 1H NMR (CDCl3) delta(ppm): 8.30 (d, J= 2.0 Hz, 1H), 8.16 (d, J= 9.3 Hz, 1H), 8.13 (dd, J = 8.7 Hz, J= 2.0 Hz, 1H), 8.04 (d, J = 8.7 Hz, 1H), 7.78 (d, J = 2.4 Hz, 1H), 7.27 (dd, J = 9.0 Hz, J = 2.4 Hz, 1H), 2.95 (s, 3H, CH3). MS (ES) m/e (M+1): 376.
939-69-5 6-Hydroxybenzo[d]thiazole-2-carbonitrile 9881912, athiazole compound, is more and more widely used in various fields.
Reference:
Patent; Promega Corporation; HUANG, Fen; KLAUBERT, Dieter; SHULTZ, John; ZHOU, Wenhui; (54 pag.)EP2611929; (2016); B1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica