1123-55-3, Benzo[d]thiazol-7-amine is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
1123-55-3, A mixture of 1, 3-BENZOTHIAZOL-7-AMINE (Description 43,30 mg, 0.2 mmol) and [4- (trifluoromethyl) benzyl] isocyanate (Description 3,40 mg, 0.2 mmol) in DCM (2 ml) was stirred at room temperature for 18 h. TLC analysis showed minimal reaction therefore 1,2-dichloroethane (1 ml) was added and the mixture was heated at 80C for 4 h. N, N-DIMETHYLFOM-LAMIDE (0.25 ml) was then added and the mixture was heated at 80C for 18 h. The mixture was then cooled to room temperature and stirred at this temperature for 2 h. The mixture was filtered to give the title compound as a white solid (28 mg, 40%). 1H NMR (d6 DMSO, 400 MHz) 8 9.33 (1H, s), 8.74 (1H, s), 7.82 (1H, d, J7. 9), 7.73 (3H, m), 7.55 (2H, d, J 8. 0), 7.45 (1H, t, J 8. 0), 7.10 (1H, br. t, J 5.9), 4.44 (2H, br. d, J 5. 9). M/Z (ES+) 352 (M+H+).
As the paragraph descriping shows that 1123-55-3 is playing an increasingly important role.
Reference:
Patent; MERCK SHARP & DOHME LIMITED; WO2005/28445; (2005); A2;,
Thiazole | C3H3NS – PubChem
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