31785-05-4, Ethyl 5-amino-2-methylthiazole-4-carboxylate is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Synthesis of compound 2 (5-amino-2-methylthiazolor5,4-o1pyrimidin-7-ol): 5-amino-2-methyl-thiazole-4-carboxylic acid ethyl ester (compound 1) (31.3 g. 0.168 mol) and cyanamide (17.5 g, 0.416 mol) were dissolved in dioxane (150 ml_, pre-dried using 4 A molecular sieves). In addition, drop wise 4 N HCI in dioxane (200 ml) was added over 15 minutes and the mixture was heated to reflux and vigorously stirred, for 5 days. The volatiles were evaporated to dryness and the crude product (55 g) was used without any further purification in the next step.
31785-05-4, The synthetic route of 31785-05-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; PFIZER PRODUCTS INC.; WO2008/59368; (2008); A2;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica