14527-43-6, Ethyl thiazole-4-carboxylate is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A solution of 13 (108.25?g, 0.689?mol) in THF (344?mL) was added dropwise to a suspension of LiAlH4 (26.3?g, 0.692?mmol) in THF (344?mL) at 0?C. The reaction mixture was stirred for 30?min?at 0?C (at this point TLC indicated consumption of the SM). It was then quenched by successive addition of EtOAc (50?mL), water (26?mL), 10% NaOH (26?mL) solution, and water (78?mL) (the temperature should not exceed 0?C). The precipitate was filtered and washed several times with THF. The filtrate was evaporated to give 8, which was used without purification. M?=?43.25?g. Yield?=?54%., 14527-43-6
The synthetic route of 14527-43-6 has been constantly updated, and we look forward to future research findings.
Reference：
Article; Curreli, Francesca; Belov, Dmitry S.; Kwon, Young Do; Ramesh, Ranjith; Furimsky, Anna M.; O’Loughlin, Kathleen; Byrge, Patricia C.; Iyer, Lalitha V.; Mirsalis, Jon C.; Kurkin, Alexander V.; Altieri, Andrea; Debnath, Asim K.; European Journal of Medicinal Chemistry; vol. 154; (2018); p. 367 – 391;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica