With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.3622-38-6,2-Chloro-5-nitrobenzo[d]thiazole,as a common compound, the synthetic route is as follows.
Step: 100 mg, 0.67 mmol of benzo[c][1,2]oxaborol-1,5(3H)-diol was dissolved in 8 mL of acetonitrile.Then, 172 mg, 0.8 mmol of 2-chloro-5-nitrobenzothiazole and 329.1 mg, 1.01 mmol of cesium carbonate were added, and the mixture was stirred at 50 ° C overnight, cooled to room temperature, then added with water, and the solid was precipitated, and the crude product solid was prepared. Purification by phase separation to give 5-(5-nitrobenzothiazol-2-oxy)benzo[c][1,2]oxaborol-1(3H)-ol as a white solid 15 mg. The yield was 6.8percent., 3622-38-6
The synthetic route of 3622-38-6 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Guangzhou Baiting Pharmaceutical Technology Co., Ltd.; Wu Zhong; Li Jingrong; (16 pag.)CN108997394; (2018); A;,
Thiazole | C3H3NS – PubChem
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