Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 159326-69-9, is researched, Molecular C5H7N3O, about Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase, the main research direction is isosteric proline replacement pyrrolo triazine inhibitor IGF1R kinase structure.SDS of cas: 159326-69-9.
Pyrrolidine, pyrrolidinone, carbocyclic, and acyclic groups were used as isosteric proline replacements in a series of insulin-like growth factor I receptor kinase/insulin receptor kinase inhibitors. Examples that were similar in potency to proline-containing reference compounds were shown to project a key fluoropyridine amide into a common space, while less potent compounds were not able to do so for reasons of stereochem. or structural rigidity.
If you want to learn more about this compound(1-Aminopyrrole-2-carboxamide)SDS of cas: 159326-69-9, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(159326-69-9).
Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica