Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 83435-58-9, is researched, Molecular C10H19NO3, about Solvent free, fast and asymmetric Michael additions of ketones to nitroolefins using chiral pyrrolidine-pyridone conjugate bases as organocatalysts, the main research direction is chiral pyrrolidine pyridone conjugate base stereoselective preparation; ketone nitroolefin asym Michael addition.Quality Control of Boc-D-Prolinol.
New chiral organocatalysts are envisaged based on a pyrrolidine-pyridone conjugate and synthesized from com. available proline employing standard protocols. These catalysts were found to be useful for asym. Michael additions of ketones to nitroolefins to afford the desired products in very good yields (up to 98%) with excellent diastereo- and enantioselectivities (>97:3 syn/anti and up to 98% ee) in very short reaction time compared with the existing reports.
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Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica