The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Boc-D-Prolinol( cas:83435-58-9 ) is researched.Formula: C10H19NO3.Zoute, Ludivine; Kociok-Kohn, Gabriele; Frost, Christopher G. published the article 《Rhodium-Catalyzed 1,4-Additions to Enantiopure Acceptors: Asymmetric Synthesis of Functionalized Pyrrolizidinones》 about this compound( cas:83435-58-9 ) in Organic Letters. Keywords: pyrrolizidinone asym preparation; arylboronic acid pyrrolidinyl propenoate asym addition rhodium catalyst. Let’s learn more about this compound (cas:83435-58-9).
The rhodium-catalyzed 1,4-addition of arylboronic acids to an enantiopure heterocyclic acceptor proceeds under ligand control to effect an asym. synthesis of functionalized pyrrolizidinones. The protocol allows convenient access to all four stereoisomers of pyrrolizidinone by appropriate selection of substrate and catalyst.
This literature about this compound(83435-58-9)Formula: C10H19NO3has given us a lot of inspiration, and I hope that the research on this compound(Boc-D-Prolinol) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica