Extracurricular laboratory: Synthetic route of 83435-58-9

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Recommanded Product: Boc-D-Prolinol. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: Boc-D-Prolinol, is researched, Molecular C10H19NO3, CAS is 83435-58-9, about One-pot oxidative conversion of alcohols into nitriles by using a TEMPO/PhI(OAc)2/NH4OAc system. Author is Vatele, Jean-Michel.

A direct conversion of alcs. into nitriles with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO), iodosobenzene diacetate, and ammonium acetate as a nitrogen source is reported. This transformation, which proceeds through an oxidation-imination-aldimine oxidation sequence in situ, has been applied to a range of aliphatic, benzylic, heteroaromatic, allylic and propargyl alcs. Highly chemoselective ammoxidation of primary alcs. in the presence of secondary alcs. was also achieved.

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Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica