Mikherdov, A. S.;Baikov, S. V.;Proskurina, I. K.;Shetnev, A. A.;Kotov, A. D. published 《Synthesis and Properties of C,N-Chelated Carbene Complexes of Palladium(II) with 2-Aminobenzo[d]thiazole Fragment》. The research results were published in《Russian Journal of General Chemistry》 in 2019.Name: 6-Nitrobenzo[d]thiazol-2-amine The article conveys some information:
The reaction of bis(cyclohexylisocyanide) complex of Pd(II) with substituted benzo[d]thiazole-2-amines in the presence of triethanolamine as the base has lead to the formation of deprotonated C,N-chelated carbene complexes with a structure similar to that described previously for the products of the reaction with unsubstituted benzo[d]thiazole-2-amine. The complexes have been isolated and characterized using high-resolution mass spectrometry, IR and NMR spectroscopy (1H, 13C{1H}, 1H-1H COSY, 1H-1H NOESY, 1H-13C HSQC, 1H-13C HMBC). The resulting complexes have exhibited moderate antibacterial activity against sensitive strains of gram-neg. bacteria E. coli (C600) and P. fluorescens (P218), gram-pos. bacteria S. aureus (ATCC-25923) and B. subtillis (B-3142D) as well as fungi C. albicans (401/NCTC-885-653).6-Nitrobenzo[d]thiazol-2-amine (cas: 6285-57-0) were involved in the experimental procedure.
6-Nitrobenzo[d]thiazol-2-amine(cas:6285-57-0 Name: 6-Nitrobenzo[d]thiazol-2-amine) is an antimicrobial agent that inhibits bacterial growth by cleaving the peptide bonds of proteins. It has been shown to be active against a number of microorganisms, including Gram-positive and Gram-negative bacteria, as well as fungi.
Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica