Name: 6-Nitrobenzo[d]thiazol-2-amine《Lemon juice mediated multicomponent reactions for the synthesis of fused imidazoles》 was published in 2018. The authors were Saha, Argha;Jana, Asim;Choudhury, Lokman H., and the article was included in《New Journal of Chemistry》. The author mentioned the following in the article:
A one-pot three component reaction mediated by lemon juice in an aqueous medium for the synthesis of diverse pharmaceutically important tricyclic fused imidazoles tethered with aryl and various cyclic 1,3-dicarbonyls was reported. The reaction of arylglyoxals with cyclic 1,3-diacarbonyls such as N-methyl-4-hydroxyquinolone, 2,4-dihydroxyquinoline, 4-hydroxycoumarin or 4-hydroxy-6-methyl-2-pyrone with various 1,3-N,N-binucleophiles such as 2-aminobenzothiazoles or 2-aminobenzimidazoles provided medicinally important diverse tricyclic fused imidazoles having aryl and cyclic 1,3-dicarbonyl substituents under metal-free conditions. This method is a natural acid catalyzed multicomponent reaction in an aqueous medium for the synthesis of diverse tricyclic fused imidazoles in good to excellent yields.6-Nitrobenzo[d]thiazol-2-amine (cas: 6285-57-0) were involved in the experimental procedure.
6-Nitrobenzo[d]thiazol-2-amine(cas:6285-57-0 Name: 6-Nitrobenzo[d]thiazol-2-amine) is an antimicrobial agent that inhibits bacterial growth by cleaving the peptide bonds of proteins. It has been shown to be active against a number of microorganisms, including Gram-positive and Gram-negative bacteria, as well as fungi.
Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica