Jana, Asim;Bhaumick, Prabhas;Panday, Anoop Kumar;Mishra, Richa;Choudhury, Lokman H. published 《I2/DMSO mediated multicomponent reaction for the synthesis of 2-arylbenzo[d]imidazo[2,1-b]thiazole derivatives》 in 2019. The article was appeared in 《Organic & Biomolecular Chemistry》. They have made some progress in their research.HPLC of Formula: 6285-57-0 The article mentions the following:
Synthesis of a series of 2-arylbenzo[d]imidazo[2,1-b]thiazoles tethered with barbituric acid moiety was reported from the three component reaction of 2-aminobenzothiazoles, barbituric acids and terminal aryl acetylenes or aryl Me ketones in the presence of I2 in DMSO medium. Both conventional and microwave heating conditions was used for this multicomponent reaction. The salient features of this methodol. are: (i) formation of one C-C and two C-N bonds in one-pot under metal-free oxidation followed by cyclization (ii) selective formation of the fused imidazole ring, (iii) wide substrate scope (iv) easy purification of the products (v) products having more than one pharmaceutically important motifs and (vi) gram scale synthesis possible.6-Nitrobenzo[d]thiazol-2-amine (cas: 6285-57-0) were involved in the experimental procedure.
6-Nitrobenzo[d]thiazol-2-amine(cas:6285-57-0) has been used:
as model analyte for voltammetric determination of electrochemically reducible organic substances;
in the synthesis of 2-methyl-4-nitro-2H-pyrazole-3-carboxylic acid[2-(cyclohexanecarbonylamino)benzothiazol-6-yl]amide derivatives;
in the preparation of push-pull nonlinear optical chromophores containing thiazole and benzothiazole acceptors;
as a base in dye production by diazotation reaction.
Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica