Recommanded Product: 6285-57-0《Synthesis, spectroscopic characterization and biological evaluation of some 6-nitro-benzothiazole-2-yl-hydrazone derivatives》 was published in 2018. The authors were Kolate, S. S.;Waghulde, G. P.;Patil, C. J.;Sarode, C. H., and the article was included in《Journal of Pharmaceutical, Chemical and Biological Sciences》. The author mentioned the following in the article:
A series of 2-[(6-Nitro-benzothiazol-2-yl)-hydrazonomethyl]-substituted-phenol derivatives I [R = 3-MeO, 5-Br, 4-diethylamino, etc.] were synthesized and characterized by using elemental and spectroscopic analyses (FT-IR, UV-Vis, 1H-NMR, 13C-NMR and Mass spectra). The synthesized compounds I were screened for antimicrobial activities against two Gram-pos. bacteria (Bacillus subtilis and Streptomyces griseus) two Gramneg. bacteria (Salmonella typhi and Pseudomonas aeruginosa) and three funguses (Candidi tropicalis, Kluyveromyces marxianus and Saccharomyces cerevisiae). The antioxidant activities of these compounds I were determined by hydrogen peroxide (H2O2) scavenging activity. The substitution iodo-group compound I [R = 3,5-diiodo] was more potentially active than other synthesized compounds I in antibacterial and antifungal activities and the most promising antioxidant activity showed by compounds I [3-MeO, 4-MeO]. The experimental procedure involved many compounds, such as 6-Nitrobenzo[d]thiazol-2-amine (cas: 6285-57-0) .
6-Nitrobenzo[d]thiazol-2-amine(cas:6285-57-0 Recommanded Product: 6285-57-0) inhibits the activity of amines, which are small molecules found in many pharmaceuticals. The chemical structure of this drug contains one or more methylene groups that can be activated by diazonium salt to form an intermediate molecule with a reactive amine group.
Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica