Chan, Christina;Foster, Sean T.;Chan, Kayla G.;Cacace, Matthew J.;Ladd, Shay L.;Sandum, Caleb T.;Wright, Paul T.;Volmert, Brett;Yang, Weiyang;Aguirre, Aitor;Li, Wen;Wright, Neil T. published 《Repositioned Drugs for COVID-19-the Impact on Multiple Organs》 in 2021. The article was appeared in 《SN Comprehensive Clinical Medicine》. They have made some progress in their research.HPLC of Formula: 55981-09-4 The article mentions the following:
Abstract: This review summarizes published findings of the beneficial and harmful effects on the heart, lungs, immune system, kidney, liver, and central nervous system of 47 drugs that have been proposed to treat COVID-19. Many of the repurposed drugs were chosen for their benefits to the pulmonary system, as well as immunosuppressive and anti-inflammatory effects. However, these drugs have mixed effects on the heart, liver, kidney, and central nervous system. Drug treatments are critical in the fight against COVID-19, along with vaccines and public health protocols. Drug treatments are particularly needed as variants of the SARS-Cov-2 virus emerge with some mutations that could diminish the efficacy of the vaccines. Patients with comorbidities are more likely to require hospitalization and greater interventions. The combination of treating severe COVID-19 symptoms in the presence of comorbidities underscores the importance of understanding the effects of potential COVID-19 treatments on other organs. To complete the study, the researchers used 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate (cas: 55981-09-4) .
2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate(cas: 55981-09-4), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans.HPLC of Formula: 55981-09-4
Reference:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica