Deng, Xiao-Bing; Chen, Ning; Wang, Zhi-Xin; Li, Xin-Yao; Hu, Hong-Yan; Xu, Jia-Xi published the artcile< A Convenient Synthesis of Thiazolidin-2-ones from Thiazolidine-2-thiones: Antibiotic Activity and Revisiting the Mechanism>, Electric Literature of 171877-39-7, the main research area is thiazolidinone preparation antifungal antibacterial activity; thiazolidinethione bromoethanol reactant thiazolidinone preparation.
Various substituted thiazolidin-2-ones were synthesized from the corresponding thiazolidine-2-thiones with bromoethanol in ethanol with sodium ethoxide as a base. The optimal reaction conditions and mechanism were reinvestigated in detail. The bioassay indicated that (S)-4-iso-butylthiazolidin-2-one and (S)-4-benzylthiazolidin-2-one show certain inhibitive activities against Candida albicans and Escherichia coli.
Phosphorus, Sulfur and Silicon and the Related Elements published new progress about Antibacterial agents. 171877-39-7 belongs to class thiazole, and the molecular formula is C10H11NS2, Electric Literature of 171877-39-7.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica