Love, Anna C.; Prescher, Jennifer A. published the artcile< Seeing (and Using) the Light: Recent Developments in Bioluminescence Technology>, Application In Synthesis of 2591-17-5, the main research area is review luciferase luciferin bioluminescence optical imaging; bioluminescence; imaging; luciferase; luciferin; optogenetics.
A review. Bioluminescence has long been used to image biol. processes in vivo. This technol. features luciferase enzymes and luciferin small mols. that produce visible light. Bioluminescent photons can be detected in tissues and live organisms, enabling sensitive and noninvasive readouts on physiol. function. Traditional applications have focused on tracking cells and gene expression patterns, but new probes are pushing the frontiers of what can be visualized. The past few years have also seen the merger of bioluminescence with optogenetic platforms. Luciferase-luciferin reactions can drive light-activatable proteins, ultimately triggering signal transduction and other downstream events. This review highlights these and other recent advances in bioluminescence technol., with an emphasis on tool development. We showcase how new luciferins and engineered luciferases are expanding the scope of optical imaging. We also highlight how bioluminescent systems are being leveraged not just for sensing-but also controlling-biol. processes.
Cell Chemical Biology published new progress about Bioluminescence. 2591-17-5 belongs to class thiazole, and the molecular formula is C11H8N2O3S2, Application In Synthesis of 2591-17-5.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica