In 2021,Songklanakarin Journal of Science and Technology included an article by Sriset, Yollada; Chatuphonprasert, Waranya; Jarukamjorn, Kanokwan. Synthetic Route of C18H24N6O6S4. The article was titled 《In vitro antioxidant potential of Mallotus repandus (Willd.) Muell. Arg stem extract and its active constituent bergenin》. The information in the text is summarized as follows:
Mallotus repandus (MR) is used in Thai traditional medicine recipes for anti-inflammation and adaptive homeostasis. Bergenin is the bioactive constituent in MR stem. This study evaluated the in vitro antioxidant activity of bergenin and the methanol, ethanol, and water extracts of MR stem prepared by maceration and Soxhlet extraction by assaying 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS•+), hydroxyl (•OH), superoxide (•O2), and nitric oxide (NO•) radical scavenging activities and ferric reducing antioxidant power. Bergenin had the highest ferric reducing power and all the MR extracts showed concentration-dependent ferric reducing power. Methanol and water extracts showed superior radical scavenging activities compared to ethanol extract The water and methanol Soxhlet extracts demonstrated the highest ABTS•+ and •OH radical scavenging activities, resp., and the macerated water extract had the lowest •O2 and NO•; IC50 values. Therefore, MR stem and bergenin are promising natural candidates for developing antioxidant supplements. The experimental part of the paper was very detailed, including the reaction process of ABTS Diammonium(cas: 30931-67-0Synthetic Route of C18H24N6O6S4)
ABTS Diammonium(cas: 30931-67-0) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Synthetic Route of C18H24N6O6S4
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica