Luescher, Michael U.; Bode, Jeffrey W. published the artcile< Catalytic Synthesis of N-Unprotected Piperazines, Morpholines, and Thiomorpholines from Aldehydes and SnAP Reagents>, Reference of 1003-32-3, the main research area is SnAP reagent aldehyde copper PhBox catalyst heterocyclization; piperazine morpholine thiomorpholine preparation; SnAP reagents; aldehydes; cross-coupling; homogeneous catalysis; nitrogen heterocycles.
Com. available SnAP (stannyl amine protocol) reagents allow the transformation of aldehydes and ketones into a variety of N-unprotected heterocycles, i.e. I. By identifying new ligands and reaction conditions, a robust catalytic variant that expands the substrate scope to previously inaccessible heteroaromatic substrates and new substitution patterns was realized. It also establishes the basis for a catalytic enantioselective process through the use of chiral ligands.
Angewandte Chemie, International Edition published new progress about Aromatic imines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1003-32-3 belongs to class thiazole, and the molecular formula is C4H3NOS, Reference of 1003-32-3.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica