Villa, Reymundo; Mandel, Alexander L.; Jones, Brian D.; La Clair, James J.; Burkart, Michael D. published the artcile< Structure of FD-895 Revealed through Total Synthesis>, SDS of cas: 171877-39-7, the main research area is FD895 synthesis structure antitumor.
The total synthesis of FD-895 (I) was completed through a strategy that featured the use of a tandem esterification ring-closing metathesis (RCM) process to construct the 12-membered macrolide and a modified Stille coupling to append the side chain. These studies combined with detailed anal. of all four possible C16-C17 stereoisomers were used to confirm the structure of FD-895 and identify an analog with an enhanced subnanomolar bioactivity.
Organic Letters published new progress about Absolute configuration. 171877-39-7 belongs to class thiazole, and the molecular formula is C10H11NS2, SDS of cas: 171877-39-7.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica