Vyzhdak, R. N.; Danielova, A. A.; Kiselev, V. V.; Drach, B. S. published the artcile< Derivatives of 5-(Dimethylamino)-4-tosyl-1,3-oxazole-2-carbaldehyde and Its Analogs>, Category: thiazole, the main research area is oxazolecarbaldehyde amino tosyl preparation condensation.
Treatment of N-(2,2,2-trichloro-1-tosylethyl)dichloroacetamide with excess Me2NH, piperidine, or morpholine gave substituted aminals of the oxazole series, whose facile acid hydrolysis provided 5-(dimethylamino)-4-tosyl-1,3-oxazole-2-carbaldehyde and its analogs having the piperidino and morpholino group in the 5-position of the oxazole ring. The resulting aldehydes and their aminals were condensed with PhN2H3, thiosemicarbazide, N-alkylrhodanines, and 1,3-dimethylbarbituric acid to obtain 2,5-disubstituted 4-tosyl-1,3-oxazoles.
Russian Journal of General Chemistry published new progress about Cyclization. 10574-69-3 belongs to class thiazole, and the molecular formula is C10H9NOS2, Category: thiazole.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica