Davidsson, Oejvind’s team published research in Bioorganic & Medicinal Chemistry Letters in 2020 | CAS: 97817-23-7

4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine(cas: 97817-23-7) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.Recommanded Product: 4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine

Davidsson, Oejvind; Nilsson, Kristina; Braanalt, Jonas; Andersson, Terese; Berggren, Kristina; Chen, Yantao; Fjellstroem, Ola; Graden, Henrik; Gustafsson, Linda; Hermansson, Nils-Olov; Jansen, Frank; Johannesson, Petra; Ohlsson, Bengt; Tyrchan, Christian; Wellner, Annika; Wellner, Eric; Oelwegaard-Halvarsson, Maria published an article on February 15 ,2020. The article was titled 《Identification of novel GPR81 agonist lead series for target biology evaluation》, and you may find the article in Bioorganic & Medicinal Chemistry Letters.Recommanded Product: 4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine The information in the text is summarized as follows:

GPR81 is a novel drug target that is implicated in the control of glucose and lipid metabolism The lack of potent GPR81 modulators suitable for in vivo studies has limited the pharmacol. characterization of this lactate sensing receptor. We performed a high throughput screen (HTS) and identified a GPR81 agonist chem. series containing a central acyl urea scaffold linker. During SAR exploration two addnl. new series were evolved, one containing cyclic acyl urea bioisosteres and another a central amide bond. These three series provide different selectivity and physicochem. properties suitable for in-vivo studies. In the experiment, the researchers used many compounds, for example, 4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine(cas: 97817-23-7Recommanded Product: 4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine)

4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine(cas: 97817-23-7) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.Recommanded Product: 4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica