In 2005,Kitagawa, Tokujiro; Asada, Makoto published 《Preparation and root growth-inhibitory activity of N-substituted 2-(2-chloroacetamido)-3-(furan-2-yl)propanamides》.Chemical & Pharmaceutical Bulletin published the findings.HPLC of Formula: 3034-22-8 The information in the text is summarized as follows:
A series of N-substituted 2-(2-chloroacetamido)-3-(furan-2-yl)propanamides, e.g., I, was prepared through the reaction of chloroacetyl chloride with N-substituted 2-amino-3-(furan-2-yl)propanamides, which were obtained by condensation of 2-(tert-butoxycarbonylamido)-3-(furan-2-yl)propanoic acid (Boc-furylalanine) with amines, followed by hydrolysis of the resultant N-substituted Boc-furylalanine acid amides in the presence of HCl/dioxane. The biol. activity of the prepared compounds as root growth inhibitors was examined by germination assay using rape seed. At the concentration of 5.0 × 10-5 M, the most active compound, 2-(2-chloroacetamido)-N-(2,6-diethylphenyl)-3-(furan-2-yl)propanamide (I), showed potent root growth-inhibitory activity of 76% towards rape seedlings. After reading the article, we found that the author used 5-Bromothiazol-2-amine(cas: 3034-22-8HPLC of Formula: 3034-22-8)
5-Bromothiazol-2-amine(cas: 3034-22-8) belongs to anime. Left-handed and right-handed forms (mirror-image configurations, known as optical isomers or enantiomers) are possible when all the substituents on the central nitrogen atom are different (i.e., the nitrogen is chiral). With amines, there is extremely rapid inversion in which the two configurations are interconverted.HPLC of Formula: 3034-22-8
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica