Kearney, Patrick C.; Fernandez, Monica; Flygare, John A. published the artcile< Traceless Solid-Phase Synthesis of 2-Aminothiazoles>, Synthetic Route of 57493-24-0, the main research area is thiazolamine derivative preparation solid phase; ketone bromo cyclocondensation resin bound thiourea.
2-Aminothiazoles are produced under mild conditions in good yields and with high degrees of purity from a primary amine and an α-bromo ketone. The key to this method is the conversion of a resin-bound amino group to a thiourea using Fmoc-NCS.
Journal of Organic Chemistry published new progress about Cyclocondensation reaction. 57493-24-0 belongs to class thiazole, and the molecular formula is C9H7N3O2S, Synthetic Route of 57493-24-0.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica