Plouvier, Bertrand’s team published research in Heterocycles in 1991-04-01 | 72054-60-5

Heterocycles published new progress about 72054-60-5. 72054-60-5 belongs to class thiazole, and the molecular formula is C7H10N2O2S, Application of C7H10N2O2S.

Plouvier, Bertrand; Bailly, Christian; Houssin, Raymond; Henichart, Jean Pierre published the artcile< Synthesis of two new thiazole-containing oligopeptides as potential DNA minor groove binding analogs of netropsin>, Application of C7H10N2O2S, the main research area is netrospin thiazole analog DNA binding.

On the basis of previous studies on synthetic models related to the antibiotic agents netropsin and distamycin A, the design and synthesis of two potential DNA minor groove ligands I and II are described. I and II were prepared by liquid-phase peptide synthesis from the key compounds Et 2-amino-5-methylthiazole-4-carboxylate and Et 2-aminothiazole-5-carboxylate, resp.

Heterocycles published new progress about 72054-60-5. 72054-60-5 belongs to class thiazole, and the molecular formula is C7H10N2O2S, Application of C7H10N2O2S.

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica