Durant, Graham J.; Ganellin, C. Robin; Parsons, Michael E. published the artcile< Chemical differentiation of histamine H1- and H2-receptor agonists>, Category: thiazole, the main research area is histamine analog receptor agonist.
Histamine [51-45-6] H1- and H2-receptor agonist activities of 10 histamine derivatives and analogs were determined and related to chem. structure and tautomeric form. Nontautomeric 2-(2-aminoethyl)thiazole-2HCl (I-2HCl) [56933-57-4] and 2-(2-aminoethyl)pyridine-2HCl (II-2HCl) [3343-39-3] are highly selective H1-receptor agonists (H1:H2 ∼90:1 and 30:1, resp.), while 4-methylhistamine-2HCl [36376-47-3] is a selective H2-receptor agonist.
Journal of Medicinal Chemistry published new progress about Receptors Role: BIOL (Biological Study). 1003-32-3 belongs to class thiazole, and the molecular formula is C4H3NOS, Category: thiazole.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica