Category: thiazoleIn 2019 ,《3(2H)-pyridazinone derivatives: a new scaffold for novel plant activators》 appeared in RSC Advances. The author of the article were Shi, Qinjie; Shi, Yanxia; Chang, Kang; Chen, Jianqin; Zhao, Zhenjiang; Zhu, Weiping; Xu, Yufang; Li, Bao Ju; Qian, Xuhong. The article conveys some information:
Due to the emergence of drug resistance, pesticide residue and environmental contamination, it is important to develop novel eco-friendly strategies to protect plants. Among them, plant activators have been gaining more and more attention. Herein, based on SHAFTS method, a new scaffold for novel plant activators was predicted and the discovery and structure-activity relationships of a series of 3(2H)-pyridazinone derivatives as novel plant activators were elucidated in detail. The vast majority of compounds exhibited excellent broad-spectrum induced resistance activity against tested diseases in vivo but no direct antimicrobial activity in vitro. Among them, compound 32 showed excellent efficacy against four pathogens and great potential as new plant activators in crop protection. The experimental process involved the reaction of 5-Bromothiazol-2-amine(cas: 3034-22-8Category: thiazole)
5-Bromothiazol-2-amine(cas: 3034-22-8) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Category: thiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica