Johnson, Jino; Yardily, A. published an article in 2020, the title of the article was Synthesis, spectral investigation, thermal, molecular modeling and bio-molecular docking studies of a thiazole derived chalcone and its metal complexes.Application of 24295-03-2 And the article contains the following content:
A thiazole-based chalconoid ligand (E)-3-(2-hydroxyphenyl)-1-(thiazol-2-yl)prop-2-en-1-one (HPTP) and its Co(II), Ni(II), Cu(II) and Zn(II) complexes have been synthesized. The synthesized compounds were characterized by elemental anal., molar conductance, UV-visible, FTIR, NMR, mass spectral techniques, magnetic susceptibility, powder XRD and SEM with EDAX. In addition, the structures were optimized with D. Functional Theory (DFT) computations. The Lewis base nature of HPTP, stability on coordination, charge transfer interactions, quantum chem. parameters and vibrational frequencies were analyzed. The mols. were docked with 5FX6 receptor as possible inhibitors of human rhinovirus (HRV) 3 C protease. The experimental process involved the reaction of 2-Acetylthiazole(cas: 24295-03-2).Application of 24295-03-2
The Article related to transition metal hydroxyphenyl thiazolyl propenone schiff base complex preparation, optimized mol structure transition metal schiff base complex, nonlinear optical property transition metal schiff base complex, thermal stability magnetic property transition metal schiff base complex and other aspects.Application of 24295-03-2
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica