Vibhute, Prashant K.; Aghao, Arvind K.; Jadhav, Satish B.; Dawane, Bhaskar S. published an article in 2021, the title of the article was Design, synthesis and characterization of some novel thiazole and quinoline containing schiff bases and evaluation of their in-vitro anti-inflammatory and antimicrobial activity.Category: thiazole And the article contains the following content:
A novel and eco-friendly series of quinoline based Schiff bases I [R = H, 4-Cl, 4-Br, etc.] in PEG-400 were synthesized. It contd. two pharmacol. active nucleus i.e. 8-hydroxyquinoline and 4-substituted phenylthiazole. The targeted compounds were obtained in good yield by reacting 2-amino-4-substituted phenylthiazole with 8-hydroxyquinoline-2-carbaldehyde which was obtained by oxidative product of 8-hydroxy-2-Me quinoline. The mol. structures of the synthesized compounds I were confirmed by physicochem. properties and spectral characteristics (IR, NMR, elemental anal. and Mass spectra). The synthesized compounds I were screened for the in-vitro anti-inflammatory and antimicrobial activity. Thiazole quinoline Schiff base could be a promising mol. in developing area of antimicrobial agents for modern pharmacologists and chemists. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Category: thiazole
The Article related to hydroxyquinoline carbaldehyde phenylthiazole diastereoselective schiff imination green chem, phenylthiazolyliminomethyl quinolinol preparation antiinflammatory antibacterial antifungal and other aspects.Category: thiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica