On December 26, 2017, Mai, Xi; Feng, Lihua; Liao, Yijing; Xu, Zhaoxing published a patent.SDS of cas: 64987-16-2 The title of the patent was Purine hydroxamic acid derivative and its preparation method and application in preparing drug for treating histone deacetylases mediated disease. And the patent contained the following:
The title purine hydroxamic acid derivative has structural formula I, wherein R1 is H or Me; R2 is H, halogen, alkyl, alkoxyl, alkylamino, hydroxyl, cyano or nitro. The derivative and its pharmaceutical composition can be used in preparing drug for treating histone deacetylases mediated disease, and has obvious inhibiting effect on histone deacetylases and anti-tumor activity. The experimental process involved the reaction of Methyl 2-(2-aminothiazol-4-yl)acetate(cas: 64987-16-2).SDS of cas: 64987-16-2
The Article related to purine hydroxamic acid preparation histone deacetylase antitumor, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.SDS of cas: 64987-16-2
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica