Shaikh, Majid; Shaikh, Mujahed; Sheikh, Anis Ahmed; Kasim, Sayyad Sultan published an article in 2021, the title of the article was Synthesis of 4-aryl-2-aminothiazole using onion extract:a green chemistry approach.Formula: C9H8N2S And the article contains the following content:
The novel green and cost effective protocol was described for the synthesis of most important thiazole moiety by using onion extract as efficient solvent. The synthesis was performed by reaction between acetophenones and N-bromosuccinamide in onion juice medium followed by addition of thiourea. The easy work up ,shorter reaction time , environmentally benign and good to excellent yield of product were some specific features of this protocol. The results obtained were tabulated. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Formula: C9H8N2S
The Article related to acetophenone bromosuccinimide thiourea cyclocondensation ultrasonication green chem, amino phenylthiazole preparation, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Formula: C9H8N2S
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica