On January 24, 1985, there was a patent about blood platelet.Application of 64987-16-2 The title of the patent was Alkyl 2-substituted amino-4-thiazolylacetates. And the patent contained the following:
The title esters I [R, R1 = 5-(1-imidazolyl)pentyl, Me; cyclohexylamino, Me; EtNH, Et] were prepared by reaction of II with the corresponding carboxylic acids or isocyanates. I had platelet aggregation inhibitory activity at 5-25 mg/kg-day. Thus, a mixture of 6-(1-imidazolyl)hexanoic acid 0.9, 1-hydroxybenzotriazole 0.7, and DCC 1 g in DMF was stirred 30 min at 40-50°, 0.9 g II (R1 = Me) in DMF added, and the whole stirred 1 h at 40-50% to give I [R = 5-(1-imidazolyl)pentyl, R1 = Me]. The experimental process involved the reaction of Methyl 2-(2-aminothiazol-4-yl)acetate(cas: 64987-16-2).Application of 64987-16-2
The Article related to aminothiazolylacetate blood platelet aggregation, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Application of 64987-16-2
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica