On June 15, 1983, Kamiya, Takashi published a patent.Synthetic Route of 64987-16-2 The title of the patent was Thiazole derivatives. And the patent contained the following:
The title compds I and II (R = COCO2H; R1 = protected amino, alkylamino; R2 = H, halo) were prepared Thus, 14 g I (R = 4-EtO2CCH2, R1 = 2-NH2, R2 = H) was acylated with EtCMe2O2CCl to give 12 g III (R3 = CH2CO2Et). This (0.3 g) was oxidized with SeO2 to give 0.22 g III (R3 = COCO2Et), which (2.8 g) was saponified to give 1.75 g III (R3 = COCO2H). I and II are intermediates in preparation of antibiotic 3-cephem-4-carboxylic acid derivatives The experimental process involved the reaction of Methyl 2-(2-aminothiazol-4-yl)acetate(cas: 64987-16-2).Synthetic Route of 64987-16-2
The Article related to aminothiazoleglycolate, thiazoleglycolate amino, thiazoleacetate amino oxo, cephalosporin intermediate aminothiazoleglycolate, Biomolecules and Their Synthetic Analogs: Beta-Lactam Fungal Metabolites and other aspects.Synthetic Route of 64987-16-2
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica