White, Lisa J.; Boles, Jessica E.; Hilton, Kira L. F.; Ellaby, Rebecca J.; Hiscock, Jennifer R. published an article in 2020, the title of the article was Towards the application of supramolecular self-associating amphiphiles as next-generation delivery vehicles.Quality Control of 2-(4-Aminophenyl)-6-methylbenzothiazole And the article contains the following content:
Herein, we present a series of supramol. self-associating amphiphilic (SSA) salts and establish the potential for these mol. constructs to act as next-generation solution-state mol. delivery vehicles. We characterize the self-association of these SSAs, both alone and when co-formulated with a variety of drug(like) competitive guest species. Single crystal X-ray diffraction studies enable the observation of hydrogen-bonded self-association events in the solid state, while high resolution mass spectrometry confirms the presence of anionic SSA dimers in the gas-phase. These same anionic SSA dimeric species are also identified within a competitive organic solvent environment (DMSO-d6/0.5% H2O). However, extended self-associated aggregates are observed to form under aqueous conditions (H2O/5.0% EtOH) in both the absence and presence of these competitive guest species. Finally, through the completion of these studies, we present a framework to support others in the characterization of such systems. The experimental process involved the reaction of 2-(4-Aminophenyl)-6-methylbenzothiazole(cas: 92-36-4).Quality Control of 2-(4-Aminophenyl)-6-methylbenzothiazole
The Article related to drug delivery self associating amphiphile, amphiphile, drug delivery, hydrogen bond, supramolecular chemistry, Pharmaceuticals: Formulation and Compounding and other aspects.Quality Control of 2-(4-Aminophenyl)-6-methylbenzothiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica