On August 31, 1987, Yoshioka, Mitsuru published an article.Synthetic Route of 64987-16-2 The title of the article was Synthetic studies related to oral β-lactam antibiotics. And the article contained the following:
A review. Review with 10 references on the development of an industrial process for producing 7432-S (I), a new oral cephem in 36-42% overall yields from penicillin G. The experimental process involved the reaction of Methyl 2-(2-aminothiazol-4-yl)acetate(cas: 64987-16-2).Synthetic Route of 64987-16-2
The Article related to review cephem 7432 s manufacture, Biomolecules and Their Synthetic Analogs: Reviews and other aspects.Synthetic Route of 64987-16-2
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica