On January 31, 2004, Muri, E. M. F.; Mishra, H.; Stein, S. M.; Williamson, J. S. published an article.Recommanded Product: 64987-16-2 The title of the article was Molecular modeling, synthesis and biological evaluation of heterocyclic hydroxamic acids designed as Helicobacter pylori urease inhibitors. And the article contained the following:
A computer-generated homol. model of the antimicrobial target Helicobacter pylori urease was derived, using the x-ray crystal structure of Klebsiella aerogenes as a template, in order to design novel urease inhibitors. Based on these computational studies, several heterocyclic hydroxamic acid derivatives have been designed, synthesized, and examined for their ability to inhibit urease activity. The experimental process involved the reaction of Methyl 2-(2-aminothiazol-4-yl)acetate(cas: 64987-16-2).Recommanded Product: 64987-16-2
The Article related to helicobacter urease inhibitor heterocyclic hydroxamate derivative preparation, Pharmacology: Structure-Activity and other aspects.Recommanded Product: 64987-16-2
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica