On September 30, 1991, Sheth, Hasmukh B.; Sporns, Peter published an article.Synthetic Route of 64987-16-2 The title of the article was Development of a single ELISA for detection of sulfonamides. And the article contained the following:
A sulfathiazole derivative was chem. linked to proteins in such a way that the aromatic amino group, common to all sulfonamides, was distal to the protein. A subset of the antibodies developed against this immunization conjugate could be used competitively with different sulfonamide haptens, linking methods and proteins to develop ELISA methods that had a broad spectrum of sulfonamide recognition. By use of the best ELISA protocol, 9 different sulfonamides decreased absorbance values 50% at concentrations <2 nM per assay. The sulfonamides recognized by the competitive ELISA had similar steric characteristics but considerable variation in electronic configuration. The method may be developed for screening of foods and related materials. The experimental process involved the reaction of Methyl 2-(2-aminothiazol-4-yl)acetate(cas: 64987-16-2).Synthetic Route of 64987-16-2
The Article related to sulfonamide determination food, immunoassay sulfonamide, elisa sulfonamide, Food and Feed Chemistry: Analysis and other aspects.Synthetic Route of 64987-16-2
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica