Day: November 9, 2022

Li, Yongyi; Yao, Wanyou; Ou, Shuilian; Huang, Xuezhen published an article in 2019, the title of the article was Correlation analysis of APTT, PT and other coagulation related indicators with the occurrence of prethrombus in pregnant women.Electric Literature of 92-36-4 And the article contains the following content:

Objective To analyze the changes of activated partial thromboplastin time (APTT), prothrombin time (PT) and other coagulation related indexes in pregnant women with prethrombus state during pregnancy, and to explore the correlation between them. Methods 60 pregnant women with prethrombotic condition (diagnosed by ultrasound) and 100 normal pregnant women who underwent phys. examination in the Department of Obstetrics and Gynecol. of our hospital from Jan. 2017 to Oct. 2018 were enrolled as study subjects. They were divided into the prethrombotic condition group and the normal pregnancy group. The prethrombotic status indicators of pregnant women in the two groups were detected by ELISA: d-dimer (D-D). Immunoturbidimetry method was used to detect coagulant function indexes, such as prothrombin time (PT), activated partial clotting enzyme live time (APTT), thrombin time (TT), fibrinogen (FBG) and antithrombin III (AT-III) . These indexes of the two groups of pregnant women were compared and analyzed by correlation method, which provided the basis for expounding the correlation between the changes of coagulation function indexes and the occurrence of prethrombus state. Results There was no significant difference in TT, PT and FBG between prethrombus state group and normal pregnancy group (P>0.05). APTT and AT-III in the prethrombus state group was (22.4±3.3) s and (76.3±5.7) %, which was lower than those in the normal pregnancy group (26.4±2.1) s and (92.3±6.4) %, which was neg. correlated with the occurrence of prethrombus state, with statistically significant difference (P<0.05). The D-D level in the prethrombotic condition group was higher than that in the normal pregnancy group, which was pos. correlated with the occurrence of prethrombotic state, and the difference was statistically significant (P<0.05). Conclusion The anomaly of APTT, AT-III and D-D is an important index to suggest the occurrence of prethrombotic state, and thus checking for changes of their levels is of great significance for predicting early pregnancy thrombosis and making reasonable delivery plan. The experimental process involved the reaction of 2-(4-Aminophenyl)-6-methylbenzothiazole(cas: 92-36-4).Electric Literature of 92-36-4

2-(4-Aminophenyl)-6-methylbenzothiazole(cas:92-36-4) belongs to thiazole. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. Electric Literature of 92-36-4

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

King, L. Carroll; Hlavacek, Robert J. published an article in 1950, the title of the article was Reaction of ketones with iodine and thiourea.Formula: C9H7IN2S And the article contains the following content:

cf. C.A. 42, 6360f. The ketone (0.1 mol.), 0.2 mol. CS(NH2)2, and 0.1 mol. iodine, heated overnight on the steam bath, give the substituted 2-aminothiazole; the cooled reaction product is extracted with ether, the residue in boiling H2O filtered, the filtrate made alk. with concentrated NH4OH, and the precipitate crystallized from aqueous EtOH; if the product is an oil, it is crystallized from Skellysolve C. The m.ps. of the Ac derivatives are given in parentheses. 4-Substituted 2-aminothiazoles: p-chlorophenyl, m. 163-4°, 89% [254-5°]; p-bromophenyl, m. 180-1°, 93% [277-8°]; p-iodophenyl, m. 176-7°, 97% [302-3°]; p-methoxyphenyl, m. 204-5°, 72% [287-8°]; p-(methylmercapto)phenyl, m. 180-2°, 67% [232-3°]; p-aminophenyl, m. 174-5°, 63% [di-Ac derivative, m. 284-6°]; p-biphenylyl, m. 207-8°, 99% [252-3°]; p-tolyl, m. 124-5°, 84% [204-5°]; m-isomer, m. 79-92°, 64% [211-12°]; o-isomer, m. 81-2°, 70% [143-4°]; p-nitrophenyl, m. 285-6°, 99% [306-7°]; m-isomer, m. 188-90°, 84% [312-14°]; 2-naphthyl, m. 153-4°, 99% [239-40°]; 2-phenanthryl, m. 243-4°, 87% [304-5°]; 2-thienyl, m. 127-30°, 91% [199-207°]; tert-Bu, m. 98-9°, 71% [173-4°]; ο-hydroxyphenyl, m. 139-40°, 37% [di-Ac derivative, m. 200-3°; HI salt, m. 220-3° (each HI salt has 1 mol. H2O)]; m-isomer, m. 136-8°, 59% [di-Ac derivative, 186-7°; HI salt, 95-7°]; p-isomer, m. 198-200°, 62% [di-Ac derivative, m. 235-7°; HI salt m. 240-2°]; 4-phenyl-5-Et, m. 68-9°, 65% [175-6°]; 4-phenyl-5-Bu, m. 103-4°, 54% [135-6°]; 4-phenyl-5-Bu, m. 60-1°, 43% [187-8°]; 4-benzyl-5-Ph, m. 139-40°, 83% [164-5°]; 4,5-di-Ph, m. 184-5°, 99% [208-9°]; 4-phenyl-5-benzoyl, m. 215-16°, 18% [237-8°]. The aminothiazole from 4-methylcyclohexanone, C8H12N2S, m. 98-9°, 66% [162-3°]; the 3-isomer gives 24% 2-amino-5(or -7)-methyl-4,5,6,7 -tetrahydrobenzothiazole, m. 110-11° [150-1°]. Compound from cycloheptanone, C8H12N2S, m. 75-6° 60% [124-5°]; from hydrindone, C10H8N2S, m. 213-14°, 53% [284-5°]; from 3,4-dihydro-1(2H)-naphthalenone, m. 133-4°, 52% [233-4°]; acenaphthenone gives 99% 8-aminoacenaphtho-1,2-thiazole, bright red, m. 205-7° [309-11°]. Bromoacetomesitylene (4.6 g.) yields 3.8 g. 2,4,6-trimethylphenacylisothiuronium bromide, m. 280-2°; it could not be cyclized to a thiazole. The experimental process involved the reaction of 2-Amino-4-(4-iodophenyl)thiazole(cas: 31699-14-6).Formula: C9H7IN2S

2-Amino-4-(4-iodophenyl)thiazole(cas:31699-14-6) belongs to thiazole. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. Formula: C9H7IN2S

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On December 31, 2021, Rodda, Michele; Niissalo, Matti A. published an article.Computed Properties of 92-36-4 The title of the article was Plastome evolution and organisation in the Hoya group (Apocynaceae). And the article contained the following:

Abstract: The genus Hoya is highly diverse and many of its species are popular ornamental plants. However, the relationships between Hoya and related genera (the Hoya group) are not fully resolved. In this study, we report 20 newly sequenced plastomes of species in the Hoya group. The complete plastomes vary in length from 175,405 to 178,525 bp while the LSCs vary from 90,248 to 92,364 bp and the complete SSCs vary from 2,285 to 2,304 bp, making the SSC in the Hoya group one of the shortest known in the angiosperms. The plastome structure in the Hoya group is characterised by a massive increase in the size of the inverted repeats as compared to the outgroups. In all ingroup species, the IR/SSC boundary moved from ycf1 to ndhF while this was not observed in outgroup taxa, making it a synapomorphy for the Hoya group. We have also assembled the mitogenome of Hoya lithophytica, which, at 718,734 bp, is the longest reported in the family. The phylogenetic anal. using exons from 42 taxa in the Hoya group and three outgoups confirms that the earliest divergent genus in the Hoya group is Papuahoya, followed by Dischidia. The relationship between Dischidia and the clade which includes all Hoya and Oreosparte taxa, is not fully supported. Oreosparte is nested in Hoya making it paraphyletic unless Clemensiella is recognized as a sep. genus. The experimental process involved the reaction of 2-(4-Aminophenyl)-6-methylbenzothiazole(cas: 92-36-4).Computed Properties of 92-36-4

2-(4-Aminophenyl)-6-methylbenzothiazole(cas:92-36-4) belongs to thiazole. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. Computed Properties of 92-36-4

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Covello, Mario; De Simone, Francesco; Dini, Antonio published an article in 1968, the title of the article was New iodinated organic compounds. (Iodophenyl)thiazoles.Application In Synthesis of 2-Amino-4-(4-iodophenyl)thiazole And the article contains the following content:

Iodinated ketones were converted to their α-Br derivatives, condensed with H2NCSNH2 in refluxing Me2CO, and neutralized with NH4OH to 2-aminothiazoles (I) (Ar and R given): p-IC6H4, H; p-IC6H4, Me; 2,,5-MeOIC6H3, H; 2,3,5-MeOI2C6H2, H; 4,3,5-HOI2C6H2, H; 4,3,5-MeOI2C6H2, H; 4,3,5-HOI2C6H2, Me; and 4,3,5-MeOI2C6H2, Me. The experimental process involved the reaction of 2-Amino-4-(4-iodophenyl)thiazole(cas: 31699-14-6).Application In Synthesis of 2-Amino-4-(4-iodophenyl)thiazole

2-Amino-4-(4-iodophenyl)thiazole(cas:31699-14-6) belongs to thiazole. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. Application In Synthesis of 2-Amino-4-(4-iodophenyl)thiazole

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On April 8, 2022, Kumar, K Suresh; Suganthi, N; Muppidi, Satish; Kumar, B Santhosh published an article.Product Details of 92-36-4 The title of the article was FSPBO-DQN: SeGAN based segmentation and Fractional Student Psychology Optimization enabled Deep Q Network for skin cancer detection in IoT applications.. And the article contained the following:

Skin cancer is one of the dangerous types of cancer and the rate of death is increasing due to the lack of knowledge in prevention and the symptoms. It is a common cancer type around the world and it occurs when the skin cells are damaged. Hence, the detection of skin cancer near the beginning is important to prevent the spread of cancer and to increase the survival rate. Recently, image processing and machine learning techniques gained more interest in medical applications. However, early analysis of skin cancer images is very challenging due to factors, like variations in the color illumination, light reflections from the skin surface, and different sizes and shapes of lesions. To detect skin cancer at an early stage and to increase the survival rate, an effective skin cancer detection method is introduced in this study using the proposed Fractional Student Psychology Based Optimization-based Deep Q Network (FSPBO-based DQN) in the wireless network scenario. At first, the nodes simulated in the network area are allowed to capture the healthcare information to make the detection strategy using the proposed method. Then, the routing is performed by the proposed Fractional Student Psychology Based Optimization (FSPBO) algorithm by considering the fitness parameters, like distance, energy, trust, and delay. After the images (healthcare information) are reached the Base Station (BS), the pre-processing, segmentation, and cancer detection processes are carried out to detect the skin lesions. Initially, the image is fed to pre-processing phase, where a Type II Fuzzy System and cuckoo search optimization algorithm (T2FCS) filter is employed to remove the noise of images. Then, the pre-processed images are fed to the segmentation phase, where speech enhancement Generative Adversarial Network (SeGAN) is used to generate the segmented results. Afterward, the Deep Q Network (DQN) detects the skin cancer based on the segmented results, and the training of DQN is made using the proposed FSPBO algorithm, which is designed by integrating the Student Psychology Based Optimization (SPBO) and Fractional Calculus (FC). The proposed method is more robust and reduces computation time and complexity. Moreover, the proposed method achieved higher performance by considering the measures, namely accuracy, sensitivity, and specificity with the values of 92.364%, 93.20%, and 92.63%. The experimental process involved the reaction of 2-(4-Aminophenyl)-6-methylbenzothiazole(cas: 92-36-4).Product Details of 92-36-4

The Article related to deep q network, fractional calculus, internet of things, routing, skin cancer detection, algorithms, humans, image processing, computer-assisted: methods, skin neoplasms: diagnostic imaging, speech, students and other aspects.Product Details of 92-36-4

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On December 4, 2020, Ludwig, Cassie A; Perera, Chandrashan; Myung, David; Greven, Margaret A; Smith, Stephen J; Chang, Robert T; Leng, Theodore published an article.Reference of 2-(4-Aminophenyl)-6-methylbenzothiazole The title of the article was Automatic Identification of Referral-Warranted Diabetic Retinopathy Using Deep Learning on Mobile Phone Images.. And the article contained the following:

Purpose: To evaluate the performance of a deep learning algorithm in the detection of referral-warranted diabetic retinopathy (RDR) on low-resolution fundus images acquired with a smartphone and indirect ophthalmoscope lens adapter. Methods: An automated deep learning algorithm trained on 92,364 traditional fundus camera images was tested on a dataset of smartphone fundus images from 103 eyes acquired from two previously published studies. Images were extracted from live video screenshots from fundus examinations using a commercially available lens adapter and exported as a screenshot from live video clips filmed at 1080p resolution. Each image was graded twice by a board-certified ophthalmologist and compared to the output of the algorithm, which classified each image as having RDR (moderate nonproliferative DR or worse) or no RDR. Results: In spite of the presence of multiple artifacts (lens glare, lens particulates/smudging, user hands over the objective lens) and low-resolution images achieved by users of various levels of medical training, the algorithm achieved a 0.89 (95% confidence interval [CI] 0.83-0.95) area under the curve with an 89% sensitivity (95% CI 81%-100%) and 83% specificity (95% CI 77%-89%) for detecting RDR on mobile phone acquired fundus photos. Conclusions: The fully data-driven artificial intelligence-based grading algorithm herein can be used to screen fundus photos taken from mobile devices and identify with high reliability which cases should be referred to an ophthalmologist for further evaluation and treatment. Translational Relevance: The implementation of this algorithm on a global basis could drastically reduce the rate of vision loss attributed to DR. The experimental process involved the reaction of 2-(4-Aminophenyl)-6-methylbenzothiazole(cas: 92-36-4).Reference of 2-(4-Aminophenyl)-6-methylbenzothiazole

The Article related to artificial intelligence, deep learning, diabetic retinopathy, fundus photography, mobile technology, artificial intelligence, deep learning, diabetes mellitus, diabetic retinopathy: diagnosis, humans, referral and consultation, reproducibility of results and other aspects.Reference of 2-(4-Aminophenyl)-6-methylbenzothiazole

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

McDonald, Sarah D; Pullenayegum, Eleanor; Chapman, Barbara; Vera, Claudio; Giglia, Lucia; Fusch, Christoph; Foster, Gary published an article in 2012, the title of the article was Prevalence and predictors of exclusive breastfeeding at hospital discharge..COA of Formula: C14H12N2S And the article contains the following content:

OBJECTIVE: To estimate the population-based prevalence and predictors of exclusive breastfeeding at hospital discharge in singleton and twin term newborns. METHODS: We studied all hospital births in the province of Ontario, Canada, between April 1, 2009, and March 31, 2010, to perform a retrospective cohort study. We included live singleton and twin births, at term (37 0/7 weeks of gestation to 41 6/7 weeks of gestation), with information about feeding at maternal-newborn discharge. Descriptive statistics were performed and logistic regression was used to identify factors related to exclusive breastfeeding. RESULTS: Our study population consisted of 92,364 newborns, of whom 56,865 (61.6%) were exclusively breastfed at discharge. Older, nonsmoking, higher-income mothers with no pregnancy complications or reproductive assistance were more likely to breastfeed. Mothers of twins were less likely to exclusively breastfeed (adjusted odds ratio [OR] 0.30, 95% confidence interval [CI] 0.25-0.36) as were women who did not attend prenatal classes (adjusted OR 0.80, 95% CI 0.76-0.83). Compared with patients of obstetricians (57%), women cared for by midwives (87%, adjusted OR 4.49, 95% CI 4.16-4.85) and family physicians (67%, adjusted OR 1.54, 95% CI 1.47-1.61) were more likely to exclusively breastfeed. Breastfeeding after a planned (50%, adjusted OR 0.56, 95% CI 0.52-0.60) or unplanned (48%, adjusted OR 0.48, 95% CI 0.44-0.51) cesarean delivery was less common than after a spontaneous vaginal birth (68%). Neonates born at 39, 38, and 37 weeks of gestation (compared with 41 weeks of gestation) were increasingly less likely to breastfeed (adjusted ORs 0.93, 95% CI 0.89-0.98; 0.84, 95% CI 0.80-0.88; and 0.71, 95% CI 0.67-0.76). CONCLUSION: This large population-based study found that fewer than two thirds of term newborns are exclusively breastfed at hospital discharge, substantially lower than previously reported. LEVEL OF EVIDENCE: II. The experimental process involved the reaction of 2-(4-Aminophenyl)-6-methylbenzothiazole(cas: 92-36-4).COA of Formula: C14H12N2S

The Article related to adult, breast feeding: statistics & numerical data, female, humans, incidence, infant, newborn, male, ontario: geographic, ontario: epidemiology, patient discharge, prevalence, retrospective studies, social class and other aspects.COA of Formula: C14H12N2S

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On August 3, 2013, Lutsiv, Olha; Giglia, Lucia; Pullenayegum, Eleanor; Foster, Gary; Vera, Claudio; Chapman, Barbara; Fusch, Christoph; McDonald, Sarah D published an article.Electric Literature of 92-36-4 The title of the article was A population-based cohort study of breastfeeding according to gestational age at term delivery.. And the article contained the following:

OBJECTIVE: Because breastfeeding is the optimal form of infant feeding, this study was conducted to determine the effect of gestational age on breastfeeding in term infants. STUDY DESIGN: A retrospective population-based cohort study of singleton/twin hospital births was conducted in Ontario, Canada between April 1, 2009, and March 31, 2010. Multivariate logistic regression was used to determine the adjusted effect of gestational age on breastfeeding. RESULTS: Our study population comprised 92,364 infants, of whom 80,297 (86.9%) were exclusively or partially breastfed at the time of hospital discharge. Multivariate logistic regression analyses demonstrated that early-term infants had lower odds of being breastfed compared with infants born at 41 weeks gestation (40 weeks: aOR, 0.93; 95% CI, 0.86-0.99; 39 weeks: aOR, 0.87; 95% CI, 0.81-0.93; 38 weeks: aOR, 0.81; 95% CI, 0.75-0.88; 37 weeks: aOR, 0.74; 95% CI, 0.67-0.82). CONCLUSION: Using a population-based approach, we found that infants born at 40, 39, 38, and 37 weeks gestation had increasingly lower odds of being breastfed compared with infants born at 41 weeks. Clinicians need to be made aware of the differences in outcomes of infants delivered at early and late term, so that appropriate breastfeeding support can be provided to women at risk for not breastfeeding. The experimental process involved the reaction of 2-(4-Aminophenyl)-6-methylbenzothiazole(cas: 92-36-4).Electric Literature of 92-36-4

The Article related to adult, breast feeding: statistics & numerical data, cohort studies, female, gestational age, humans, infant, newborn, multivariate analysis, odds ratio, ontario: geographic, registries, retrospective studies, social class, term birth and other aspects.Electric Literature of 92-36-4

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Burger, Alfred; Sawhney, S. N. published an article in 1968, the title of the article was Antimalarials. III. Benzothiazole amino alcohols.Computed Properties of 19989-66-3 And the article contains the following content:

Amino alcs. carrying a CHOH(CH2)1-3NR2 chain in position 6 of a benzothiazole nucleus, unsubstituted or substituted by Ph or CF3 in the 2 position, have been synthesized by standard methods and tested for activity against Plasmodium berghei in mice. Several of the amino alcs. showed weak antimalarial activity but only at toxic doses. 15 references. The experimental process involved the reaction of Benzo[d]thiazol-6-ylmethanol(cas: 19989-66-3).Computed Properties of 19989-66-3

The Article related to amino alcohols: chemical synthesis, amino alcohols: therapeutic use, amino alcohols: toxicity, animals, antimalarials: chemical synthesis, antimalarials: therapeutic use, antimalarials: toxicity, mice, thiazoles: chemical synthesis, thiazoles: therapeutic use and other aspects.Computed Properties of 19989-66-3

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

On July 17, 2013, Lutsiv, O; Pullenayegum, E; Foster, G; Vera, C; Giglia, L; Chapman, B; Fusch, C; McDonald, S D published an article.Recommanded Product: 92-36-4 The title of the article was Women’s intentions to breastfeed: a population-based cohort study.. And the article contained the following:

OBJECTIVE: Given that intention to breastfeed is a strong predictor of breastfeeding initiation and duration, the objectives of this study were to estimate the population-based prevalence and the factors associated with the intention to breastfeed. DESIGN: Retrospective population-based cohort study. SETTING: All hospitals in Ontario, Canada (1 April 2009-31 March 2010). POPULATION: Women who gave birth to live, term, singletons/twins. METHODS: Patient, healthcare provider, and hospital factors that may be associated with intention to breastfeed were analysed using univariable and multivariable regression. MAIN OUTCOME MEASURES: Population-based prevalence of intention to breastfeed and its associated factors. RESULTS: The study included 92,364 women, of whom 78,806 (85.3%) intended to breastfeed. The odds of intending to breastfeed were higher amongst older women with no health problems and women who were cared for exclusively by midwives (adjusted OR 3.64, 95% CI 3.13-4.23). Being pregnant with twins (adjusted OR 0.73, 95% CI 0.57-0.94), not attending antenatal classes (adjusted OR 0.58, 95% CI 0.54-0.62), having previous term or preterm births (adjusted OR 0.79, 95% CI 0.78-0.81, and adjusted OR 0.87, 95% CI 0.82-0.93, respectively), and delivering in a level-1 hospital (adjusted OR 0.85, 95% CI 0.77-0.93) were associated with a lower intention to breastfeed. CONCLUSIONS: In this population-based study ~85% of women intended to breastfeed their babies. Key factors that are associated with the intention to breastfeed were identified, which can now be targeted for intervention programmes aimed at increasing the prevalence of breastfeeding and improving overall child and maternal health. The experimental process involved the reaction of 2-(4-Aminophenyl)-6-methylbenzothiazole(cas: 92-36-4).Recommanded Product: 92-36-4

The Article related to adult, breast feeding: psychology, female, hospitalization: statistics & numerical data, humans, intention, maternal age, ontario: geographic, pregnancy, pregnancy, multiple: psychology, pregnancy, multiple: statistics & numerical data, pregnant women: psychology, premature birth: psychology and other aspects.Recommanded Product: 92-36-4

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica