Covello, Mario; De Simone, Francesco; Dini, Antonio published an article in 1968, the title of the article was New iodinated organic compounds. (Iodophenyl)thiazoles.Application In Synthesis of 2-Amino-4-(4-iodophenyl)thiazole And the article contains the following content:
Iodinated ketones were converted to their α-Br derivatives, condensed with H2NCSNH2 in refluxing Me2CO, and neutralized with NH4OH to 2-aminothiazoles (I) (Ar and R given): p-IC6H4, H; p-IC6H4, Me; 2,,5-MeOIC6H3, H; 2,3,5-MeOI2C6H2, H; 4,3,5-HOI2C6H2, H; 4,3,5-MeOI2C6H2, H; 4,3,5-HOI2C6H2, Me; and 4,3,5-MeOI2C6H2, Me. The experimental process involved the reaction of 2-Amino-4-(4-iodophenyl)thiazole(cas: 31699-14-6).Application In Synthesis of 2-Amino-4-(4-iodophenyl)thiazole
2-Amino-4-(4-iodophenyl)thiazole(cas:31699-14-6) belongs to thiazole. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. Application In Synthesis of 2-Amino-4-(4-iodophenyl)thiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica