Mugherli, Laurent; Burchak, Olga N.; Balakireva, Larissa A.; Thomas, Aline; Chatelain, Francois; Balakirev, Maxim Y. published an article in 2009, the title of the article was In Situ Assembly and Screening of Enzyme Inhibitors with Surface-Tension Microarrays.Synthetic Route of 64987-16-2 And the article contains the following content:
Hundreds of reactions were conducted in parallel in droplets maintained on a glass slide through differential surface tension in a new approach to submicroliter-scale synthesis. This surface-tension microarray was applied to the in situ assembly of thousands of derivatives of phenylboronic acid and their profiling against the NS3/4A protease of the hepatitis C virus. Several potent inhibitors of the enzyme were identified. The experimental process involved the reaction of Methyl 2-(2-aminothiazol-4-yl)acetate(cas: 64987-16-2).Synthetic Route of 64987-16-2
The Article related to drug screening ns3 4a protease inhibitor preparation microarray, Pharmacology: Methods and other aspects.Synthetic Route of 64987-16-2
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica