On September 1, 2019, Sami, Yuichi; Morita, Masataka; Kubota, Hirokazu; Hirabayashi, Ryoji; Seo, Ryushi; Nakagawa, Nobuaki published an article.Synthetic Route of 2010-06-2 The title of the article was Discovery of a novel orally active TRPV4 inhibitor: Part 1. Optimization from an HTS hit. And the article contained the following:
Novel oral TRPV4 inhibitors were prepared and their potential for pain management in osteoarthritis discussed. The experimental process involved the reaction of 4-Phenylthiazol-2-amine(cas: 2010-06-2).Synthetic Route of 2010-06-2
The Article related to oral trpv4 inhibitor preparation analgesic osteoarthritis, Pharmacology: Structure-Activity and other aspects.Synthetic Route of 2010-06-2
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica