Darekar, N. R. published the artcileMicrowave Assisted Synthesis and Antibacterial Activity of New 1,3,4-Thiadiazoles and 1,2,4-Triazoles Derived from 2-{2-[2-(4-Fluorophenyl)-4-methylthiazol-5-yl]-1H-benzo[d]imidazol-1-yl}acetohydrazide, Recommanded Product: 2-(4-Fluorophenyl)-4-methylthiazole-5-carboxylic acid, the main research area is phenyl fluorophenyl methylthiazolyl benzoimidazolyl acetyl thiosemicarbazide preparation antibacterial; methyl phenyl fluorophenyl methylthiazolyl benzoimidazolyl triazole thiol preparation antibacterial; fluorophenyl methylthiazolyl benzoimidazolyl methyl phenyl thiadiazol amine preparation antibacterial; microwave irradiation.
A series of novel derivatives of 1-(2-{2-[2-(4-fluorophenyl)-4-methylthiazol-5-yl]-1H-benzo[d]imidazol-1-yl}acetyl)-4-phenylthiosemicarbazide, 5-({2-[2-(4-fluorophenyl)-4-methylthiazol-5-yl]-1H-benzo[d]imidazol-1-yl}methyl)-4-phenyl-4H-1,2,4-triazole-3-thiol and 5-({2-[2-(4-fluorophenyl)-4-methylthiazol-5-yl]-1H-benzo[d]imidazol-1-yl}methyl)-N-phenyl-1,3,4-thiadiazol-2-amine was synthesized by the conventional method as well as using MW irradiation All newly synthesized compounds were tested for antibacterial activity. Several products were demonstrated moderate activity against gram pos. and gram neg. bacterial strains.
Russian Journal of General Chemistry published new progress about Antibacterial agents. 144060-99-1 belongs to class thiazole, name is 2-(4-Fluorophenyl)-4-methylthiazole-5-carboxylic acid, and the molecular formula is C11H8FNO2S, Recommanded Product: 2-(4-Fluorophenyl)-4-methylthiazole-5-carboxylic acid.
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica