Ouimet, Nathalie published the artcileSubstituted heterocyclic analogs as selective COX-2 inhibitors in the flosulide class, SDS of cas: 5053-24-7, the publication is Bioorganic & Medicinal Chemistry Letters (1999), 9(2), 151-156, database is CAplus and MEDLINE.
Substituted heterocyclic analogs in the flosulide class were investigated as potential selective cyclooxygenase-2 inhibitors. 6-(4-Ethyl-2-thiazolylthio)-5-methanesulfonamido-3H-isobenzofuran-1-one was the optimal compound in the series with superior in vitro and in vivo anti-inflammatory activities.
Bioorganic & Medicinal Chemistry Letters published new progress about 5053-24-7. 5053-24-7 belongs to thiazole, auxiliary class Thiazole,sulfides, name is 2-(Methylthio)thiazole, and the molecular formula is C4H5NS2, SDS of cas: 5053-24-7.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica